Analysis of Risk Factors For Dry Eye Disease Among Educational Staff of The Faculty of Medicine, Muslim University of Indonesia Using The Ocular Surface Disease Index (OSDI) Questionnaire
Main Article Content
Abstract
Background: Dry eye disease is a common ocular health problem that can impair comfort, visual performance, and work productivity, particularly in occupational environments.
Aim: This study aimed to analyze factors associated with the occurrence of dry eye disease among educational staff at the Faculty of Medicine, Universitas Muslim Indonesia.
Methods: An analytical cross-sectional study was conducted using structured questionnaires and standardized symptom assessment to evaluate sex, age, duration of digital device use, air conditioner exposure, smoking habits, and dry eye disease status, followed by bivariate and multivariate statistical analyses.
Results: Smoking habits and air conditioner exposure were associated with a statistically significant increase in the occurrence of dry eye disease. Age did not demonstrate a significant association but tended to aggravate the effects of other risk factors. Sex and duration of digital device use were not significantly associated with dry eye disease; however, female sex and excessive digital device use appeared to increase susceptibility.
Conclusions: Environmental and lifestyle factors, particularly smoking exposure and prolonged use of air conditioners, play an important role in the development of dry eye disease among educational staff.
Implication: These findings highlight the need for preventive strategies that improve workplace environmental conditions and promote healthier lifestyle behaviors to reduce the burden of dry eye disease in occupational settings.
Article Details

This work is licensed under a Creative Commons Attribution 4.0 International License.
References
Aggarwal S, Galor A. What’s new in dry eye disease diagnosis? Current advances and challenges. F1000Res. 2018;7:1952. doi:10.12688/f1000research.16468.1
Allwihan R, Alhalwani AY, Khojah M, et al. The impact of electronic device use on dry eye disease symptoms based on age and gender: a cross-sectional study in health science university students. Open Ophthalmol J. 2024;18(1):e18743641330774240909052623. doi:10.2174/0118743641330774240909052623
Amparo F, Schaumberg DA, Dana R. Comparison of two questionnaires for dry eye symptom assessment. Ophthalmology. 2015;122(7):1498–1503. doi:10.1016/j.ophtha.2015.02.037
Baudouin C, Aragona P, Messmer EM, et al. Role of hyperosmolarity in the pathogenesis and management of dry eye disease: proceedings of the OCEAN Group Meeting. Ocul Surf. 2013;11(4):246–258. doi:10.1016/j.jtos.2013.07.003
Britten-Jones AC, Wang MTM, Samuels I, Jennings C, Stapleton F, Craig JP. Epidemiology and risk factors of dry eye disease: considerations for clinical management. Medicina (Kaunas). 2024;60(9):1458. doi:10.3390/medicina60091458
Craig JP, Nichols KK, Akpek EK, et al. TFOS DEWS II definition and classification report. Ocul Surf. 2017;15(3):276–283. doi:10.1016/j.jtos.2017.05.008
Dougherty BE, Nichols JJ, Nichols KK. Rasch analysis of the Ocular Surface Disease Index (OSDI). Invest Ophthalmol Vis Sci. 2011;52(12):8630–8635. doi:10.1167/iovs.11-8027
Farrand KF, Fridman M, Stillman IÖ, Schaumberg DA. Prevalence of diagnosed dry eye disease in the United States among adults aged 18 years and older. Am J Ophthalmol. 2017;182:90–98. doi:10.1016/j.ajo.2017.06.033
Garvin TJ. Book review: Surgical management of urologic disease: an anatomic approach. N Engl J Med. 1993;328(8):590–591. doi:10.1056/NEJM199302253280822
Greenan E, Murphy CC, Ní Gabhann-Dromgoole J. Optimising the method for isolating ocular surface microRNA using impression cytology. Ocul Surf. 2021;22:83–85. doi:10.1016/j.jtos.2021.07.010
Itoh Y, Inoue M, Rii T, Hiraoka T, Hirakata A. Significant correlation between visual acuity and recovery of foveal cone microstructures after macular hole surgery. Am J Ophthalmol. 2012;153(1):111–119.e1. doi:10.1016/j.ajo.2011.05.039
Pastor-Zaplana JÁ, Borrás F, Gallar J, Acosta MC. OSDI questions on daily life activities allow detection of subclinical dry eye in young contact lens users. J Clin Med. 2022;11(9):2626. doi:10.3390/jcm11092626
Pult H, Wolffsohn JS. The development and evaluation of the new Ocular Surface Disease Index-6. Ocul Surf. 2019;17(4):817–821. doi:10.1016/j.jtos.2019.08.008
Schaumberg DA, Dana R, Buring JE, Sullivan DA. Prevalence of dry eye disease among US men: estimates from the Physicians’ Health Studies. Clin Epidemiol. 2012;4:307–312. doi:10.2147/CEOR.S36352
Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol. 2000;118(5):615–621. doi:10.1001/archopht.118.5.615
Shanti Y, Shehada R, Bakkar MM, Qaddumi J. Prevalence and associated risk factors of dry eye disease in 16 northern West Bank towns in Palestine: a cross-sectional study. BMC Ophthalmol. 2020;20(1):26. doi:10.1186/s12886-019-1290-z
Song P, Xia W, Wang M, et al. Variations of dry eye disease prevalence by age, sex, and geographic characteristics in China: a systematic review and meta-analysis. J Glob Health. 2018;8(2):020503. doi:10.7189/jogh.08.020503
Stapleton F, Alves M, Bunya VY, et al. TFOS DEWS II epidemiology report. Ocul Surf. 2017;15(3):334–365. doi:10.1016/j.jtos.2017.05.003
Supiyaphun C, Jongkhajornpong P, Rattanasiri S, Lekhanont K. Prevalence and risk factors of dry eye disease among university students in Bangkok, Thailand. PLoS One. 2021;16(10):e0258217. doi:10.1371/journal.pone.0258217
The Epidemiology of Dry Eye Disease: Report of the Epidemiology Subcommittee of the International Dry Eye Workshop (2007). Ocul Surf. 2007;5(2):93–107.
Uchino M, Schaumberg DA. Dry eye disease: impact on quality of life and vision. Curr Ophthalmol Rep. 2013;1(2):51–57. doi:10.1007/s40135-013-0009-1
Uchino M, Uchino Y, Dogru M, et al. Dry eye disease and work productivity loss in visual display users: the Osaka Study. Am J Ophthalmol. 2014;157(2):294–300. doi:10.1016/j.ajo.2013.10.014
Vehof J, Snieder H, Jansonius NM, Hammond CJ. Prevalence and risk factors of dry eye in 79,866 participants of the population-based Lifelines cohort study in the Netherlands. Ocul Surf. 2021;19:83–93. doi:10.1016/j.jtos.2020.04.005
Zhang J, Begley CG, Situ P, Simpson T, Liu H. A link between tear breakup and symptoms of ocular irritation. Ocul Surf. 2017;15(4):696–703. doi:10.1016/j.jtos.2017.03.001